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kduI [2018-11-23 15:41:15]
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kduI [2018-11-23 15:41:15]

5-keto-4-deoxyuronate isomerase
Locus
BSU22130
Isoelectric point
5.11
Molecular weight
30.98 kDa
Protein length
275 aa Sequence Blast
Gene length
825 bp Sequence Blast
Function
utilization of galacturonic acid
Product
5-keto-4-deoxyuronate isomerase
Essential
no
E.C.
5.3.1.17
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of hexuronate

    • Gene

    Coordinates
    2,325,854 → 2,326,681

    The protein

    Catalyzed reaction/ biological activity

  • 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate (according to Swiss-Prot)

    • Protein family

  • PNP/MTAP phosphorylase family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    kduI-kduD
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • KdgR: repression, PubMed, in KdgR regulon
  • CcpA: repression, PubMed, in CcpA regulon

    • Regulation

  • induced by galacturonate (KdgR) PubMed
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    Biological materials

    Mutant

  • BKE22130 (ΔkduI::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTATATTTCCCCCTTGGT, downstream forward: _UP4_ATTCCAATGGATGGGCTGAA
  • BKK22130 (ΔkduI::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTATATTTCCCCCTTGGT, downstream forward: _UP4_ATTCCAATGGATGGGCTGAA

    • References

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